CaptureSelect™ AAT-XL Affinity Matrix, 50 ML

CaptureSelect™ AAT-XL Affinity Matrix, 50 ML

 CaptureSelect™ AAT-XL Affinity Matrix (50 mL) is a high-selectivity affinity chromatography resin designed for purification of native and recombinant human alpha-1 antitrypsin (AAT) from complex sources like plasma, serum, and cell culture supernatants.This affinity matrix uses a recombinant single-domain antibody fragment (VHH) ligand, ensuring high recovery and purity in a single purification step. It offers mild elution conditions at pH 6, making it ideal for gentle processing.

Specifications

• Matrix: Agarose-based, epoxide-activated

• Particle size: 65 ± 10 µm

• Ligand: CaptureSelect AAT-XL affinity ligand

• Binding capacity: 15 mg AAT/mL resin

• Elution conditions: 20 mM Tris, 2.0 M MgCl₂, pH 6.0

• Flow rate: 50–200 cm/h (up to 2 bar)

• Formulation buffer: 20% ethanol

Uses

• Purification of native and recombinant human AAT from plasma and cell culture.

• High-yield antibody purification in biopharmaceutical applications.

• Efficient removal of contaminants for improved product purity.

Features

• Highly selective binding for AAT purification.

• Mild elution conditions to preserve protein integrity.

• Scalable design for research and industrial applications.

• Animal-origin-free production for regulatory compliance.