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Product Details

Manufacturer
Fisher Scientific
SKU
10013913

About this product

N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide, 98%

This product is intended for research and development use only.

Product Details:

  • Chemical Formula: C₉H₁₈F₃NOSi

  • Molecular Weight: 241.33 g/mol

  • CAS Number: 77377-52-7

  • Appearance: Colorless to yellow liquid

  • Purity: ≥98% (GC)

  • Boiling Point: 170 °C

  • Density: 1.0200 g/mL

  • Refractive Index: 1.4010 to 1.403

  • Packaging: Available in 1 g, 5 g, and 25 g glass bottles

Applications:

  • Derivatization Reagent: Commonly used as a silylation reagent for the derivatization of various organic compounds, such as amino acids, to enhance volatility and stability for gas chromatography-mass spectrometry (GC-MS) analysis.

  • Selective O-Silylation: Employed in the selective O-silylation of N,O-diacylhydroxylamines.

  • Alkylation Reagent: Functions as an alkylation reagent in organic synthesis.

Safety Information:

  • Hazard Statements:

    • H226: Flammable liquid and vapor.

    • H315: Causes skin irritation.

    • H319: Causes serious eye irritation.

    • H335: May cause respiratory irritation.

  • Precautionary Statements:

    • P210: Keep away from heat, hot surfaces, sparks, open flames, and other ignition sources. No smoking.

    • P261: Avoid breathing dust/fume/gas/mist/vapors/spray.

    • P280: Wear protective gloves/protective clothing/eye protection/face protection.

    • P302+P352: IF ON SKIN: Wash with plenty of water.

    • P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Storage and Handling:

  • Storage Conditions: Store in a cool, well-ventilated area away from ignition sources. Keep container tightly closed.

  • Handling Precautions: Use only in a chemical fume hood. Avoid contact with skin and eyes.

Regulatory Information:

  • GHS Classification:

    • Flammable liquids (Category 3)

    • Skin corrosion/irritation (Category 2)

    • Serious eye damage/eye irritation (Category 2)

    • Specific target organ toxicity, single exposure; Respiratory tract irritation (Category 3)

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