Planova N Virus Removal Filter

Planova N Virus Removal Filter

Description

Planova N Virus Removal Filters are designed for the downstream processing of biopharmaceuticals, providing a critical safety barrier by removing viruses from biological solutions. These filters utilise a hollow-fibre membrane structure to achieve high log reduction values of both enveloped and non-enveloped viruses through size-exclusion chromatography. The technology is engineered to maintain high protein transmission and flux, ensuring efficient purification workflows in the production of plasma-derived products, recombinant proteins, and monoclonal antibodies.

Key Features

• Size-exclusion mechanism for robust removal of enveloped and non-enveloped viruses.
• Hollow-fibre membrane design optimized for high protein recovery and consistent flux.
• Scalable technology suitable for process development through to commercial manufacturing.
• Validated for high log reduction values (LRV) across a variety of viral contaminants.

Applications

• Downstream purification of monoclonal antibodies (mAbs).
• Virus clearance in the production of recombinant proteins.
• Safety filtration for plasma-derived therapeutic products.
• Bioprocess development and viral clearance validation studies.

Disclaimer

Users must ensure the specific filter grade and surface area are appropriately validated for their specific feedstream and process conditions to achieve required viral clearance targets.