Manifolds

Manifolds are critical components in bioprocessing and cell culture systems, serving as customizable fluid path assemblies that enable the controlled, sterile transfer of media, buffers, reagents, and process fluids across multiple unit operations. Commonly used in biopharmaceutical manufacturing, vaccine production, gene and cell therapy, and GMP-compliant pilot facilities, manifolds support both manual and automated workflows, ensuring sterile fluid management with minimal risk of contamination or product loss. Designed to streamline fluid handling and sampling procedures, bioprocess manifolds are composed of tubing, connectors, valves, filters, and ports arranged into pre-configured or custom-built assemblies. These systems are tailored for specific processes such as media fills, harvest collection, buffer delivery, in-process sampling, and closed system transfers. They are often manufactured as single-use assemblies, pre-sterilized via gamma irradiation, and supplied ready to integrate into closed bioprocessing systems, reducing setup time and cleaning validation requirements. Manifolds can be configured to interface with bioreactors, bags, chromatography columns, filtration units, or tangential flow filtration (TFF) systems, supporting both upstream and downstream applications. With options for multiple flow paths, sterile welds or aseptic connectors, and custom tubing lengths, they are ideal for scaling production while maintaining sterility and process consistency. Many manifolds also include built-in sampling ports that allow for real-time monitoring and quality control without breaching system integrity. Material options include TPE, platinum-cured silicone, and gamma-stable polymers, all of which comply with USP Class VI, ISO 10993, and other biopharmaceutical regulatory standards. These assemblies are engineered for compatibility with automated equipment and support lean manufacturing principles by simplifying workflows and reducing the risk of operator error. At Wasteless Bio, we provide surplus and custom-configured manifolds from leading manufacturers. Each listing includes full specifications such as flow path design, tubing type, connection method, number of ports, and sterility validation. By sourcing manifolds through Wasteless Bio, laboratories benefit from cost-effective, flexible fluid handling solutions while supporting sustainability through reuse and reduced manufacturing waste.