Mass Spectrometry

Mass spectrometry (MS) is a powerful analytical technique used for precise identification, quantification, and characterization of molecules based on their mass-to-charge ratio. It is essential in a wide range of fields including proteomics, metabolomics, pharmacokinetics, drug development, food safety, environmental science, and forensic analysis. Mass spectrometry systems provide highly sensitive, reproducible data that help researchers detect and analyze even trace amounts of compounds. At the core of every MS system is the ability to ionize a sample, separate the resulting ions by mass, and detect them to generate a spectrum. The resulting mass spectra enable the identification of proteins, peptides, metabolites, lipids, and synthetic chemicals, making MS indispensable in both basic research and regulated industries. LC-MS (Liquid Chromatography-Mass Spectrometry) combines the separation capabilities of liquid chromatography with the sensitive detection of mass spectrometry. This hybrid system is widely used for protein characterization, small molecule quantification, biomarker discovery, and drug metabolism studies. LC-MS excels in separating complex mixtures, analyzing non-volatile compounds, and profiling biofluids like plasma or urine in clinical and pharmaceutical research. It plays a central role in pharmacokinetics (PK) and ADME (Absorption, Distribution, Metabolism, and Excretion) studies. GC-MS (Gas Chromatography-Mass Spectrometry), on the other hand, is the gold standard for the analysis of volatile and semi-volatile compounds. GC-MS systems are used in environmental monitoring, toxicology, flavor and fragrance analysis, and forensic applications such as drug screening and arson investigation. The combination of chromatographic separation and MS detection ensures high sensitivity and specificity. At Wasteless Bio, we offer pre-owned, surplus MS systems including LC-MS and GC-MS models. Listings include full technical details—such as ion source type, mass range, detector type, resolution, sensitivity, and software compatibility—allowing labs to access advanced analytical platforms while supporting sustainable, circular lab procurement.