3M Zeta Plus EXT Filter

3M Zeta Plus EXT Filter

Description

The 3M Zeta Plus EXT Filter is a depth filtration solution designed for primary recovery and clarification in biopharmaceutical processes. It is used to remove cells, cell debris, and other particulate matter from fermentation broth or cell culture fluids, protecting downstream purification steps such as chromatography and membrane filtration. The filter utilizes a charge-modified depth media to enhance the removal of negatively charged contaminants, including host cell proteins and DNA, through electrokinetic adsorption.

Key Features

• Dual-layer depth filtration media for high contaminant holding capacity
• Charge-modified technology for enhanced removal of soluble impurities
• Designed to protect downstream chromatography columns and sterile filters
• Scalable format suitable for process development through to full-scale production

Applications

• Primary recovery of mammalian cell cultures
• Clarification of bacterial and yeast lysates
• Removal of host cell proteins and DNA
• Pre-filtration for sterile membrane stages

Specifications

• Media type: Charge-modified depth filter
• Application: Primary recovery and clarification
• Compatibility: Biopharmaceutical processing environments