NGL COVID-19 Spike Protein Resin 1L

The NGL COVID-19 Spike Protein Affinity Resin is designed for the efficient purification of SARS-CoV-2 Spike Protein receptor binding domain (RBD) variants. This high-performance resin enables a single-step chromatography process, achieving high purity with reduced process time, which is essential for the production of COVID-19 vaccines and other related research applications.

Key Features:

• High Purity & Yield: Effectively captures SARS-CoV-2 Spike Protein RBD variants, ensuring excellent purity and improving overall yield in vaccine production processes.
• Selectivity & Binding Capacity: Provides high dynamic binding capacity (>15 mg RBD/ml resin) at short residence times, delivering consistent and reliable results.
• Caustic Stability: With high resistance to caustic conditions, the resin remains stable across multiple cycles, enhancing the longevity of your process.
• Pre-packed & Ready-to-Use: Available in off-the-shelf OPUS® columns or loose resin formats, making it easy to integrate into your purification workflows.
• Optimized for GMP Manufacturing: Meets all expected release testing for Good Manufacturing Practice (GMP) production environments, including bioburden testing.

Specifications:

• Matrix Composition: Highly cross-linked agarose
• Ligand: Recombinant protein (E. coli expression)
• Average Particle Size: 85 µm
• Operational Pressure: Do not exceed 1.5 bar deltaP
• Operating Temperature: 4°C - 30°C
• Storage Conditions: 18-20% ethanol or 2% benzyl alcohol
• pH Range: 3 - 10 for operational use

Applications:

• Ideal for use in vaccine development, therapeutic protein purification, and related bioprocessing applications.