Isolators

Isolators are sealed containment systems designed to provide controlled environments for the handling of sterile or hazardous materials, making them indispensable in pharmaceutical production, compounding, aseptic processing, and high-containment research laboratories. These advanced systems establish physical and atmospheric barriers between the operator and the internal working space, effectively preventing contamination and ensuring both product integrity and operator safety. Pharmaceutical isolators are used extensively in sterile drug manufacturing, particularly in processes that demand aseptic conditions, such as fill-finish operations, sterility testing, vaccine preparation, and cell therapy production. By maintaining positive or negative pressure environments and utilizing HEPA-filtered airflow, isolators eliminate the need for full cleanroom classifications in some cases, significantly reducing facility costs while maintaining compliance with regulatory standards such as EU GMP Annex 1, FDA cGMP, and ISO 14644. There are two primary types of isolators: sterile (aseptic) isolators, which protect the product from external contamination, and containment isolators, which protect the user and the environment from hazardous materials like cytotoxic drugs, pathogens, or potent active pharmaceutical ingredients (APIs). Isolators often include features like integrated glove ports, vaporized hydrogen peroxide (VHP) sterilization systems, automated decontamination cycles, and touchscreen control interfaces for ease of operation and monitoring. Modern isolators are compatible with a variety of equipment such as automated filling lines, robotic arms, and environmental monitoring systems, offering a fully integrated and scalable solution for critical production environments. They also improve reproducibility and reduce human intervention, making them highly desirable for facilities seeking to increase efficiency while minimizing contamination risks. At Wasteless Bio, we offer refurbished and surplus isolators from leading manufacturers at a fraction of the original cost. Each listing includes detailed specifications such as internal volume, pressure type, airflow system, material compatibility, sterility assurance features, and regulatory compliance. By sourcing isolators through Wasteless Bio, laboratories and production facilities can ensure sterile, compliant, and sustainable operations, supporting a circular economy in life sciences.