Fluorescence Plate Readers

Fluorescence plate readers are high-sensitivity instruments designed to detect and quantify fluorescent signals in multi-well plates, enabling rapid, high-throughput analysis of biochemical and cellular assays. These systems are essential in drug discovery, genomics, proteomics, immunoassays, and clinical diagnostics, where speed, sensitivity, and reproducibility are critical. Fluorescence plate readers work by exciting fluorophores in the sample with a specific wavelength of light and measuring the emitted fluorescence at a different wavelength. This approach is ideal for detecting low-abundance biomolecules, monitoring enzyme activity, and evaluating cell health and viability. Compared to absorbance-based readers, fluorescence systems offer superior sensitivity and are often used for assays with very low target concentrations. Common applications include ELISA, qPCR, DNA/RNA quantification, protein interaction studies, reporter gene assays, and cell-based screening. Fluorescent assays are widely used in cancer biology, infectious disease research, and pharmacokinetics, making fluorescence plate readers a core component of both basic and translational research labs. Modern systems support top-read and bottom-read modes, monochromator- or filter-based detection, dual wavelength detection, and multiplexing capabilities. Many instruments also include temperature control, CO₂ regulation, and shaking options—ideal for kinetic and live-cell assays. High-end models are compatible with 384-well or 1536-well plates, enabling ultra-high-throughput workflows in pharmaceutical screening pipelines. At Wasteless Bio, we offer access to surplus and pre-owned fluorescence plate readers from trusted brands at significantly reduced prices. Listings include specifications such as wavelength range, sensitivity (z-factor), supported plate formats, reader modes, and software integration. By sourcing plate readers through Wasteless Bio, laboratories can access industry-standard analytical tools affordably—while advancing environmental sustainability and reducing procurement waste through circular science practices.