Chromium Next GEM Single Cell Multiome ATAC + Gene Expression Reagent Bundle

10x Genomics Chromium Next GEM Single Cell Multiome ATAC + Gene Expression Reagent Bundle

Description

The 10x Genomics Chromium Next GEM Single Cell Multiome ATAC + Gene Expression Reagent Bundle is designed for simultaneous profiling of the epigenome and transcriptome from the same single cell. By capturing both chromatin accessibility and gene expression data, this system enables researchers to link regulatory elements to their target genes, providing a comprehensive view of cellular heterogeneity and gene regulation mechanisms.

Key Features

• Simultaneous capture of ATAC and gene expression data from individual nuclei
• Utilises Next GEM technology for high-throughput single-cell partitioning
• Enables direct linkage of epigenetic profiles to transcriptional outputs
• Streamlined workflow for generating dual-modality sequencing libraries
• Compatible with Chromium microfluidic platforms for efficient cell processing

Applications

• Characterising complex cell populations and developmental trajectories
• Mapping gene regulatory networks in health and disease
• Investigating epigenetic drivers of differential gene expression
• Functional genomics research in oncology, immunology, and neuroscience

Specifications

• Technology: Next GEM (Gel Bead-in-emulsion)
• Analysis Type: Multiomic (ATAC and RNA-seq)
• Sample Input: Single nuclei suspensions
• Data Output: Digital Gene Expression and Chromatin Accessibility