BioSkryb ResolveDNA Library Prep Kit

BioSkryb ResolveDNA Library Prep Kit

Description

The BioSkryb ResolveDNA Library Prep Kit is designed for high-resolution genomic analysis, enabling the preparation of high-quality libraries from limited starting material. This kit utilizes Primary Template-Directed Amplification (PTA) technology to provide uniform coverage across the genome, which is essential for identifying single nucleotide variants and copy number variations with high sensitivity.

Key Features

• Utilises Primary Template-Directed Amplification (PTA) to ensure high genomic coverage and uniformity.
• Minimises amplification bias compared to traditional whole genome amplification methods.
• Enables high-fidelity sequencing results suitable for detecting low-frequency variants.
• Streamlined workflow designed for efficient library construction from amplified DNA.
• Compatible with standard downstream next-generation sequencing (NGS) platforms.

Applications

• Single-cell whole genome sequencing (WGS)
• Oncology research and somatic mutation profiling
• Preimplantation genetic testing and rare cell analysis
• Genomic heterogeneity studies in complex biological samples

Specifications

• Amplification Technology: Primary Template-Directed Amplification (PTA)
• Target Input: Low-input DNA or single-cell lysates
• Downstream Compatibility: Next-Generation Sequencing (NGS) platforms
• Application Focus: Whole Genome Sequencing (WGS)

Disclaimer

Users should ensure their specific sequencing platform and bioinformatics pipeline are compatible with PTA-based library structures.