Bruker CosMX Spatial Molecular Imager

Bruker CosMX Spatial Molecular Imager

Description

The Bruker CosMX Spatial Molecular Imager is a high-plex in situ analysis platform designed for comprehensive spatial multiomics. It enables researchers to map the distribution and expression of RNA and protein targets directly within intact tissue sections at subcellular resolution. By combining automated fluidics with high-resolution imaging, the system facilitates the exploration of cellular interactions and microenvironments without the need for tissue dissociation.

Key Features

• Subcellular resolution for precise localization of molecular targets within individual cells.
• High-plex capacity for simultaneous detection of hundreds to thousands of RNA or protein analytes.
• Non-destructive imaging process that preserves tissue morphology for integrated spatial analysis.
• Automated workflow integration from sample preparation to data acquisition.
• Compatibility with a variety of sample types including FFPE and fresh frozen tissues.

Applications

• Spatial transcriptomics and proteomics for oncology and immunology research.
• Mapping cellular atlases within complex tissue architectures.
• Investigation of the tumour microenvironment and immune cell infiltration.
• Discovery of spatially-resolved biomarkers in clinical and translational studies.