L-Arginine Monohydrochloride (Amino Acid Supplement )

L-Arginine monohydrochloride.

L-Arginine Monohydrochloride plays a crucial role in the stabilization of biologic drugs during both manufacturing and formulation. As a key chemical additive, it helps prevent protein aggregation, aids in protein refolding, and serves as an effective buffer in chromatography processes.

Designed for high-risk pharmaceutical applications, this product maintains low bioburden and endotoxin levels, ensuring superior quality and compliance with stringent regulatory standards.

Key Features:

• Product Grade: EMPROVE® EXPERT, compliant with Ph. Eur., BP, ChP, JP, USP standards
• Low Bioburden & Endotoxins: Suitable for high-risk biopharma applications
• High Purity: Ideal for use in sensitive manufacturing environments

Synonyms:

• α-Amino-δ-guanidino valerianic acid hydrochloride
• (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride
• Arg, Arginine HCl

Applications in Biopharma Manufacturing:

• Protein Refolding Additive: Enhances correct protein folding and structural stability
• Aggregate Suppression: Reduces the risk of unwanted protein aggregation during processing
• Chromatography Buffer: Improves purification efficiency in downstream bioprocessing

Biochemical/Physiological Actions:

• Nitric Oxide Synthase Substrate: Converts to citrulline and nitric oxide (NO), supporting cellular signaling pathways
• Insulin Release Induction: Stimulates insulin secretion via nitric oxide-dependent mechanisms

Regulatory Compliance:

• Conforms to major pharmacopeial standards: Ph. Eur., BP, ChP, JP, USP
• Emprove® Expert grade supports comprehensive risk assessment and regulatory filings