Product Image
More sustainable than new
$3,786.00$6,310.00Save 40%

Product Details

Manufacturer
Sartorius
SKU
98STPA42D-L

About this product

Sartobind STIC® PA Cassette, 0.8 L, 4 mm Bed Height – High-Salt Anion Exchange Membrane

Description

The Sartobind STIC® PA Cassette (0.8 L, 4 mm bed height) is a next-generation salt-tolerant interaction chromatography (STIC) device designed for high-capacity removal of process-related contaminants during monoclonal antibody (mAb) and biotherapeutic downstream processing. Engineered with a primary amine (PA) ligand on a regenerated macro-porous cellulose matrix, this membrane exhibits exceptional binding capacity in high-salt environments—eliminating the need for dilution after cation exchange (CEX) steps.

Optimized for flow-through anion exchange chromatography (AEX), the 0.8 L cassette integrates seamlessly into modular systems up to 100 L total membrane volume, offering a scalable, pod-like solution that combines disposable simplicity with column-like throughput. Ideal for host cell protein (HCP), DNA, endotoxin, and virus clearance, the STIC® PA cassette supports up to 30 bed volumes/min, accelerating process development without compromising yield or quality.

Key Features:

  • 0.8 L membrane volume with 4 mm bed height for intermediate-scale bioproduction
  • PA ligand chemistry delivers high binding capacity at up to 1.5 M NaCl
  • Modular cassette design supports up to 100 L membrane volume
  • High flow rate capability – up to 30 bed volumes/min
  • Removes HCPs up to 10 kg/L membrane, DNA, endotoxins, and viruses
  • Plug-and-play format simplifies integration and reduces validation effort
  • Disposable after single use, reducing cross-contamination risk
  • Ideal for use in mAb, vaccine, and recombinant protein purification workflows

Applications

  • Monoclonal antibody (mAb) production
  • Downstream purification of biopharmaceuticals
  • High-throughput anion exchange for contaminant removal
  • Vaccine manufacturing
  • Virus and endotoxin clearance in flow-through processes

Specifications

  • Product Name: Sartobind STIC® PA Cassette
  • Volume: 0.8 L
  • Bed Height: 4 mm
  • Ligand Type: Primary Amine (PA)
  • Matrix: Regenerated cross-linked cellulose
  • Operating Mode: Flow-through
  • Max Flow Rate: Up to 30 bed volumes/min
  • Disposable: Yes
  • Compatibility: Modular systems up to 100 L

Related Products

What Our Clients Say

Supporting innovation at leading research companies

RNAnalytics

RNAnalytics

Leading The Way In Gene Therapy Analytics

As a startup focused on developing analytical toolkits for LNP characterization, RNAnalytics operates under tight budget constraints while striving to maintain a fully stocked lab with high-quality materials. Sustainability is also a core pillar of our operations, pushing us to make environmentally conscious decisions wherever possible....