Chromatography Systems for Purification

Chromatography Systems for Purification are the cornerstone of downstream bioprocessing, enabling high-resolution separation and purification of complex biologic products such as monoclonal antibodies (mAbs), recombinant proteins, vaccines, and gene therapy vectors. These systems are essential for achieving the purity, potency, and safety required for clinical and commercial biopharmaceutical production. At Wasteless Bio, our marketplace features a wide selection of chromatography purification systems, offering affordable, sustainable access to cutting-edge purification technology from top manufacturers. These systems operate on principles of affinity, ion exchange, hydrophobic interaction, or size exclusion chromatography to isolate target molecules from process impurities. Affinity chromatography, particularly Protein A columns, is the industry gold standard for mAb capture due to its high selectivity. Ion exchange and hydrophobic interaction chromatography are typically used for intermediate and polishing steps, while size exclusion chromatography plays a key role in aggregate removal and formulation. Our catalog includes automated chromatography workstations with precise gradient control, built-in UV detectors, conductivity sensors, and fraction collectors. These features allow for tight process control, scalability, and reproducibility—critical for GMP compliance and regulatory approval. Whether you require a compact bench-scale unit for research or a fully integrated skid system for production-scale purification, Wasteless Bio provides systems to match every stage of development and manufacturing. We frequently list chromatography platforms from trusted brands such as Cytiva (formerly GE Healthcare), Bio-Rad, Thermo Fisher Scientific, Sartorius, and Agilent. These systems are compatible with a wide range of column formats and resins, making them highly adaptable to various purification protocols. Purchasing surplus or refurbished chromatography systems from Wasteless Bio not only reduces capital expenditure but also supports your lab’s sustainability initiatives by diverting quality instruments from waste. Whether you're developing a new biologic or scaling up an existing process, our chromatography purification systems deliver reliable, high-performance solutions for every purification challenge.