Sartorius Sartobind Q Membrane Adsorber Cassette

Sartorius Sartobind Q Membrane Adsorber Cassette

Description

The Sartorius Sartobind Q Membrane Adsorber Cassette is designed for the efficient removal of contaminants during downstream processing in biopharmaceutical manufacturing. Utilising ion exchange technology, these cassettes facilitate the capture of negatively charged impurities such as DNA, host cell proteins, and viruses from biological feedstreams. The membrane-based format allows for high flow rates and rapid processing compared to traditional resin-based chromatography, supporting high-throughput purification workflows.

Key Features

• Strong quaternary ammonium (Q) anion exchange chemistry for effective contaminant binding.
• Convective mass transfer mechanism enables high flow rates without compromising binding capacity.
• Scalable design allows for consistent performance from laboratory development to industrial production.
• Reduced buffer consumption and footprint compared to conventional column chromatography.
• Optimised flow path construction ensures uniform distribution across the membrane bed.

Applications

• Polishing steps in monoclonal antibody (mAb) purification.
• Removal of genomic DNA and host cell proteins from recombinant proteins.
• Viral clearance and endotoxin removal in bioprocessing.
• Fractionation of plasma proteins and vaccine purification.

Specifications

• Ligand Type: Quaternary ammonium (Q)
• Adsorption Mechanism: Strong Anion Exchange
• Format: Membrane Adsorber Cassette
• Flow Type: Convective mass transfer