10x Genomics Chromium Fixed RNA Kit Human Transcriptome

10x Genomics Chromium Fixed RNA Kit Human Transcriptome

Description

The 10x Genomics Chromium Fixed RNA Kit Human Transcriptome is designed for single-cell gene expression profiling of fixed biological samples. This kit enables researchers to preserve biological states at the point of collection, facilitating the analysis of human transcriptome data from samples that require stabilization or transport before processing. By utilizing probe-based chemistry, it allows for high-sensitivity detection of transcripts while minimizing the impact of RNA degradation common in fixed tissues.

Key Features

• Probe-based capture technology for sensitive and specific human transcriptome profiling.
• Sample fixation workflow allows for the decoupling of sample collection from library preparation.
• Compatible with single-cell isolation platforms for high-throughput genomic analysis.
• Streamlined protocol for generating sequencing-ready libraries from fixed cell or nuclei suspensions.

Applications

• Single-cell gene expression analysis of fixed human cells and nuclei.
• Clinical research involving multi-site sample collection and centralized processing.
• Transcriptomic profiling of samples where immediate processing is not feasible.
• Large-scale human cell atlas projects requiring standardized fixation protocols.