Isolators

Isolators are fully enclosed, self-contained workstations designed to create ultra-clean, contamination-free environments for handling sterile materials, pharmaceuticals, hazardous substances, or sensitive biological samples. They provide complete physical separation between operators and products, ensuring both operator protection and product sterility. Isolators are essential in pharmaceutical manufacturing, compounding, cell and gene therapy production, microbiological research, and cleanroom applications where the highest levels of sterility and containment are required. Isolators maintain positive or negative pressure differentials to prevent airborne contamination. Positive-pressure isolators protect products from external contamination, ideal for sterile compounding, aseptic filling, and cell culture. Negative-pressure isolators protect operators from hazardous materials, used in handling cytotoxic drugs, infectious agents, or potent compounds. Dual-pressure isolators can switch between modes for flexible applications. These systems feature HEPA or ULPA filtration to achieve ISO Class 5 or better air quality, integrated glove ports for manual manipulation, transfer hatches or rapid transfer ports (RTPs) for material introduction and removal, and continuous monitoring of pressure, airflow, and particulate levels. Many isolators include built-in decontamination systems using vaporized hydrogen peroxide (VHP) or other agents to sterilize the chamber between uses. Isolators are widely used in sterile drug compounding, biologics production, vaccine manufacturing, sterility testing, and handling of genetically modified organisms. They are also critical in advanced therapy medicinal product (ATMP) manufacturing, where stringent contamination control is essential for patient safety and regulatory compliance. Isolators can be customized with integrated workstations, temperature control, humidity regulation, and real-time environmental monitoring. By sourcing pre-owned isolators from Wasteless Bio, laboratories and pharmaceutical facilities benefit from high-performance contamination control solutions at reduced costs while supporting sustainable equipment reuse. Each listing includes specifications such as chamber dimensions, pressure control type, filtration efficiency, glove port configuration, transfer system, decontamination method, and compliance certifications (e.g., ISO, GMP, FDA). Isolators provide the ultimate sterile barrier for critical aseptic and containment applications.