3M™ Polisher ST, BC1020 – Single-Use Anion Exchange Purifier

3M™ Polisher ST, BC1020 – Single-Use Anion Exchange Purifier

The 3M™ Polisher ST is an advanced, single-use anion exchange (AEX) membrane adsorber designed to enhance downstream purification in biopharmaceutical manufacturing. This innovative solution effectively removes host cell proteins (HCP), DNA, viruses, and turbidity while maintaining high salt tolerance, making it an ideal alternative to traditional AEX polishing columns.

Key Features & Benefits

Multi-Mechanism Purification: Combines Q-functional nonwoven media for DNA and turbidity removal with a guanidinium-functionalized membrane for enhanced HCP and virus clearance.
High Salt Tolerance: Performs efficiently in biologically relevant operating conditions, replacing conventional AEX resins in downstream processing.
Single-Use Convenience: Eliminates cleaning and validation requirements, reducing costs and increasing efficiency.
Enhanced Biomass Production: Provides high purity and yield, making it suitable for therapeutic recombinant protein purification.

Technical Specifications

Application: Anion exchange chromatography
Filter Type: Single-use membrane adsorber
Overall Diameter: 9.49 in (24.1 cm)
Overall Height: 5.98 in (15.2 cm)
Micron Rating: 0.8 µm
Flow Rate: 1020 L/hr
End Modification: ¾ in Sanitary Connectors
Net Weight: 1.8 kg

Suggested Applications

Downstream Polishing: Efficient removal of process-related impurities, including residual DNA and HCP.
Virus Clearance: Enhances viral safety in biopharmaceutical process streams.
Handling Turbid Fluids: Maintains performance even with turbidity levels up to 40 NTU.

The 3M™ Polisher ST provides a reliable and cost-effective alternative to traditional chromatography columns, ensuring consistent and high-quality biopharmaceutical purification.

Expiration Date: 31/12/2022