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Product Details

Manufacturer
Thermo Scientific
SKU
4404334

About this product

POROS™ XS Strong Cation Exchange Resin 10 L

POROS™ XS resin is a next-generation strong cation exchange (CEX) chromatography medium that delivers both exceptional loading capacity and superior resolving power. Designed to accommodate protein loads exceeding 100 mg/mL at 5% breakthrough—even at salt conductivities up to 15 mS/cm—this resin ensures high performance under a range of challenging conditions. By pushing the limits of capacity and resolution, it represents a major advancement over traditional cation exchangers and establishes a new benchmark for CEX chromatography.

  • Optimized Pore Structure & Surface Chemistry:

    • High dynamic binding capacities across various pH and salt conditions
    • Enables smaller columns, reduced buffer use, and streamlined workflows
    • Robust salt tolerance reduces/eliminates dilution steps
  • Enhanced 50 µm Particle Design:

    • Maintains resolution across different flow rates
    • Supports effective impurity clearance in high-titer bioprocesses
    • Ensures consistent separation, protecting yield and purity
  • Rigid Polymeric Bead Construction:

    • Provides chemical and physical stability over multiple cycles
    • Simplifies handling and packing with low back pressure
    • Supports scalability and minimizes process interruptions

Offered in a 10 L format, POROS XS resin is well-suited for large-scale purification tasks in biopharmaceutical production and beyond. By combining high capacity, outstanding resolution, and resilience in elevated salt conditions, it effectively streamlines downstream workflows and lowers both cost and complexity, making it an ideal choice for modern biomanufacturing processes.

Volume: 10 L

Catalog Number: 4404334

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