NGL COVID-19 Spike Protein Resin 1L

NGL COVID-19 Spike Protein Resin 1L.

NGL COVID-19 Spike Protein Resin 1L is a specialized affinity chromatography resin developed by Repligen, designed for the efficient purification of SARS-CoV-2 Spike Protein receptor binding domain (RBD) variants. This resin is particularly valuable in vaccine production, offering high purity and yield in a single chromatography step.

Key Features

• High Selectivity and Yield: Achieves over 90% purity in a single step, streamlining the purification process for SARS-CoV-2 Spike Protein RBD variants. 

• Robust Performance: Demonstrates consistent dynamic binding capacity (DBC) and yield over multiple clean-in-place (CIP) and sanitization cycles, maintaining efficiency across extended use. 

• GMP Compliance: Meets Good Manufacturing Practice (GMP) manufacturing expectations, including bioburden and endotoxin levels, ensuring suitability for clinical and commercial vaccine production. 

• Versatile Application: Compatible with various SARS-CoV-2 variants, including Alpha, Beta, Gamma, Delta, and Omicron, making it adaptable to evolving viral strains. 

Technical Specifications

• Matrix Composition: Highly cross-linked agarose

• Ligand: Recombinant protein expressed in E. coli

• Average Particle Size: 85 µm

• Operational Pressure: Do not exceed 1.5 bar deltaP

• Operating Temperature: 4–30°C (do not freeze)

• pH Range:

  • Operational: 3–10

  • Clean-in-Place (short term): 2–13

• Storage Conditions: Store in 18–20% ethanol or 2% benzyl alcohol at 2–8

• Delivery Form: Shipped at room temperature as a 52% slurry in 18% ethanol

Purchasing Information

• Price: $18,697.83 (discounted from $31,163.05)

• Availability: Available through Wasteless Bio

• SKU: 10-SPIKE-1000

• Expiration Date: January 1, 2026