Forté Bio Octet HTX System

Forté Bio Octet HTX System

Description

The Forté Bio Octet HTX System is a high-throughput label-free analysis platform used for the rapid characterisation of biomolecular interactions. Utilising Bio-Layer Interferometry (BLI) technology, this system enables researchers to perform real-time kinetic analysis and protein quantification by monitoring the interference pattern of white light reflected from a biosensor tip. It supports automated workflows in drug discovery and development, allowing for the simultaneous analysis of multiple samples to accelerate screening and lead optimisation processes.

Key Features

• Utilises Bio-Layer Interferometry (BLI) for real-time, label-free detection of molecular interactions.
• High-throughput capacity designed for rapid protein quantification and kinetic characterisation.
• Automated sensor handling to streamline large-scale screening workflows.
• Compatible with a wide range of biosensor types for diverse analytical applications.
• Provides precise measurement of association and dissociation rates without the need for fluorescent or radioactive labels.

Applications

• High-throughput antibody screening and lead optimisation.
• Protein-protein and protein-small molecule interaction analysis.
• Quantification of recombinant proteins and antibodies in crude supernatants.
• Bioprocess monitoring and quality control in pharmaceutical manufacturing.

Specifications

• Detection Technology: Bio-Layer Interferometry (BLI)
• Analysis Type: Label-free, real-time kinetics and quantification
• Data Output: Association and dissociation rate constants (ka, kd) and affinity (KD)