Cytiva Capto Q ImpRes Ion Exchange Chromatography Resin

Cytiva Capto Q ImpRes Ion Exchange Chromatography Resin

Description

Cytiva Capto Q ImpRes is a strong anion exchange chromatography resin designed for high-resolution intermediate and polishing steps in downstream purification processes. It enables the efficient separation of proteins, nucleic acids, and other biomolecules by leveraging small bead size and high binding capacity to achieve high productivity in biopharmaceutical manufacturing.

Key Features

• High-resolution separation for effective removal of impurities such as aggregates, viruses, and host cell proteins
• Small particle size combined with high flow rates to improve process throughput
• Strong anion exchange chemistry providing robust performance across a range of pH and conductivity conditions
• Rigid matrix construction allows for high bed heights and consistent pressure-flow properties
• Optimised for large-scale manufacturing environments requiring reliable and reproducible purification

Applications

• Intermediate and polishing stages of monoclonal antibody purification
• Separation of closely related protein variants and impurities
• Purification of recombinant proteins and vaccines
• Biopharmaceutical downstream process development and scale-up

Specifications

• Matrix: Rigid, high-flow agarose
• Ion exchanger type: Strong anion
• Functional group: Quaternary ammonium
• Chemical stability: Stable in all commonly used aqueous buffers and cleaning agents
• Cleaning-in-place (CIP) compatibility: 1 M NaOH

Disclaimer

This product should be used by trained laboratory professionals. Performance may vary based on specific buffer conditions and target molecule characteristics.