Enzo Biochem Annexin V Human Recombinant Conjugate
Overview
Annexin V is a 35.8 kDa calcium-dependent phospholipid-binding protein with a high affinity for phosphatidylserine (PS). This human recombinant conjugate serves as a sensitive probe for identifying cells that have lost plasma membrane asymmetry, a characteristic marker of early-stage apoptosis.
Highlights
- High affinity binding to negatively charged phospholipids in the presence of calcium.
- Effective marker for the translocation of phosphatidylserine from the inner to the outer leaflet of the plasma membrane.
- Facilitates discrimination between apoptotic and necrotic cell populations when used with membrane-impermeant dyes.
At-a-glance
- Molecular Weight
- 35.8 kDa
- Expression System
- E. coli
- Source
- Human
- Target Antigen
- Phosphatidylserine
- Recommended Applications
- FC, IHC, IF
- Condition
- Surplus/second-hand; stored under manufacturer-recommended conditions.
Applications
This reagent is utilized in cell biology research for the detection of early apoptotic events. It is commonly employed in flow cytometry (FC) and immunofluorescence (IF) to monitor programmed cell death in various mammalian cell lines and primary cultures.
Sustainability
By rehoming surplus lab products, this listing supports waste reduction and resource efficiency.
Responsible use & safety
- Require training/authorization before use.
- Inspect before operation; do not use if safety features are compromised.
- Follow manufacturer's manual for operation and maintenance.
- Maintain appropriate aseptic technique and dispose of biohazardous materials according to local regulations.
