Krosflo KMPi TFF System

Krosflo KMPi TFF System

Description

The Krosflo KMPi TFF System is a tangential flow filtration platform designed for the automated processing of biological solutions. It is primarily used for the concentration and diafiltration of proteins, antibodies, and other biomolecules, facilitating efficient downstream purification workflows. The system utilises peristaltic pump technology to maintain controlled flow rates and pressures, ensuring gentle handling of shear-sensitive samples during the filtration process.

Key Features

• Automated process control for consistent concentration and diafiltration cycles.
• Integrated pressure monitoring to maintain membrane integrity and process safety.
• Compatible with a variety of hollow fibre and flat sheet membrane modules.
• Digital interface for real-time monitoring of critical process parameters.
• Scalable design suitable for process development and pilot-scale operations.

Applications

• Concentration and diafiltration of recombinant proteins and antibodies.
• Desalting and buffer exchange in downstream bioprocessing.
• Clarification of cell lysates and fermentation broths.
• Separation of viral particles and vaccines.