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Product Details

Manufacturer
SKU
P2B100A05
Shipped From
Switzerland

About this product

Pellicon® 2 Biomax® 100 kDa Ultrafiltration Cassette, 0.5 m²

by Sigma-Aldrich · SKU P2B100A05

Overview

The Pellicon 2 Biomax 100 kDa ultrafiltration cassette is a tangential flow filtration device featuring a void-free polyethersulfone membrane with a nominal molecular weight cut-off of 100 kDa and 0.5 m² filtration area. Designed for cassette-style tangential flow filtration, this device incorporates an A screen channel configuration and Biomax membrane technology that guards against solute leakage through microdefects while delivering high flux and superior product retention. The void-free membrane structure enables fast, high-yield processing with predictable linear scalability from laboratory to industrial-scale applications, making it suitable for concentration, diafiltration, and buffer exchange of protein solutions, polysaccharides, and virus suspensions in biopharmaceutical development and production workflows.

Highlights

  • Biomax polyethersulfone membrane with void-free composite structure eliminates solute leakage through microdefects commonly found beneath thin skins of conventional ultrafiltration membranes, ensuring product integrity and high yields
  • 100 kDa nominal molecular weight cut-off provides efficient retention of proteins and macromolecules whilst allowing smaller molecules and buffer components to pass through the membrane for effective concentration and purification applications
  • A screen channel configuration with 0.5 m² filtration area delivers optimised flow characteristics and process performance with hold-up volumes of approximately 5 mL, maximising product recovery in small to medium batch operations
  • True linear scalability enables direct scale-up from laboratory modules to industrial assemblies processing thousands of litres whilst maintaining consistent separation performance, flux rates, and product quality across all scales

At-a-glance

Product Line
Pellicon 2 Cassette
Membrane Type
Biomax (composite polyethersulfone)
Nominal Molecular Weight Cut-Off (NMWCO)
100 kDa
Filtration Area
0.5 m²
Screen Type
A screen
Membrane Structure
Void-free composite
Hold-Up Volume
Approximately 5 mL (10 mL/m²)
Format
Standard cassette for Pellicon 2 holders
Condition
Surplus/second-hand

Applications

This ultrafiltration cassette is suitable for concentration, diafiltration, and buffer exchange of protein solutions, monoclonal antibodies, polysaccharides, virus suspensions, and other biopharmaceutical products with molecular weights above 100 kDa. It is widely employed in cell culture harvest clarification, downstream protein purification, vaccine concentration, and biotherapeutic formulation across biotechnology, pharmaceutical research, and bioprocessing laboratories. The 100 kDa cut-off is particularly effective for applications requiring retention of larger proteins whilst removing salts, small peptides, and buffer components.

Sustainability

By rehoming surplus lab products, this listing supports waste reduction and resource efficiency.

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