
Product Details
- Manufacturer
- Thermo Fisher Scientific
- SKU
- 10712934
- Shipped From
- United Kingdom
About this product
Thermo Fisher Scientific 2-(Trimethylsilyl)ethoxymethyl chloride, 90%, tech., stabilized
Description
Thermo Fisher Scientific 2-(Trimethylsilyl)ethoxymethyl chloride is a versatile organosilicon reagent primarily used as a protecting group for alcohols, phenols, and nitrogen-containing heterocycles in organic synthesis. This technical-grade reagent facilitates the introduction of the SEM (2-(trimethylsilyl)ethoxymethyl) group, which is valued for its stability under a wide range of reaction conditions and its ease of removal using fluoride ions or acidic conditions.
Key Features
- Provides effective protection for hydroxyl and amino functional groups during complex multi-step syntheses.
- Stabilised formulation ensures consistent chemical reactivity and handling safety.
- Technical grade purity suitable for routine synthetic laboratory applications and scale-up processes.
- Compatible with standard anhydrous reaction environments and inert gas techniques.
Applications
- Protection of alcohols and phenols in total synthesis.
- N-protection of indoles, imidazoles, and other nitrogen heterocycles.
- Intermediate preparation in pharmaceutical and materials science research.
Specifications
- CAS Number: 76513-69-4
- Chemical Formula: C6H15ClOSi
- Purity: 90% (Technical Grade)
- Stabiliser: Included for chemical stability
- Molecular Weight: 166.72 g/mol
Disclaimer
This product is a technical-grade chemical intended for laboratory research and industrial synthesis only. It must be handled by trained personnel using appropriate personal protective equipment and fume hoods.
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