Pall Mustang Q Capsule

Pall Mustang Q Capsule

Description

The Pall Mustang Q Capsule is a high-performance anion exchange chromatography device designed for the rapid removal of contaminants and the purification of biomolecules. Utilising a strong quaternary amine functional group on a polyethersulfone membrane, this capsule facilitates high-throughput processing by allowing convective flow, which overcomes the mass transfer limitations typically associated with traditional resin-based chromatography. It is primarily used in downstream processing to capture large molecules or remove impurities such as DNA, host cell proteins, and viruses.

Key Features

• Strong quaternary amine (Q) chemistry for efficient anion exchange chromatography.
• Convective flow membrane technology enables high flow rates and rapid processing times.
• High dynamic binding capacity for large biomolecules and negatively charged contaminants.
• Scalable design allows for consistent performance from laboratory development to full-scale production.
• Disposable capsule format reduces the need for cleaning validation and cross-contamination risks.

Applications

• Polishing steps for the removal of host cell proteins and DNA.
• Viral clearance and endotoxin removal in biopharmaceutical manufacturing.
• Capture and purification of large proteins, plasmids, and viral vectors.
• Fractionation of plasma proteins and other complex biological mixtures.

Specifications

• Membrane Chemistry: Strong Anion Exchange (Quaternary Amine)
• Membrane Substrate: Polyethersulfone (PES)
• Functional Group: -CH2-N+(CH3)3
• Flow Pattern: Convective flow