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Product Details

Manufacturer
Thermo Fisher Scientific
SKU
10712934
Shipped From
United Kingdom

About this product

Thermo Fisher Scientific 2-(Trimethylsilyl)ethoxymethyl chloride, 90%, tech., stabilized

Description

Thermo Fisher Scientific 2-(Trimethylsilyl)ethoxymethyl chloride is a versatile organosilicon reagent primarily used as a protecting group for alcohols, phenols, and nitrogen-containing heterocycles in organic synthesis. This technical-grade reagent facilitates the introduction of the SEM (2-(trimethylsilyl)ethoxymethyl) group, which is valued for its stability under a wide range of reaction conditions and its ease of removal using fluoride ions or acidic conditions.

Key Features

  • Provides effective protection for hydroxyl and amino functional groups during complex multi-step syntheses.
  • Stabilised formulation ensures consistent chemical reactivity and handling safety.
  • Technical grade purity suitable for routine synthetic laboratory applications and scale-up processes.
  • Compatible with standard anhydrous reaction environments and inert gas techniques.

Applications

  • Protection of alcohols and phenols in total synthesis.
  • N-protection of indoles, imidazoles, and other nitrogen heterocycles.
  • Intermediate preparation in pharmaceutical and materials science research.

Specifications

  • CAS Number: 76513-69-4
  • Chemical Formula: C6H15ClOSi
  • Purity: 90% (Technical Grade)
  • Stabiliser: Included for chemical stability
  • Molecular Weight: 166.72 g/mol

Disclaimer

This product is a technical-grade chemical intended for laboratory research and industrial synthesis only. It must be handled by trained personnel using appropriate personal protective equipment and fume hoods.

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