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Sartorius Octet ARC Biosensors
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Product Details

Manufacturer
Sartorius
SKU
18-0060
Expiration Date
Shipped From
United Kingdom

About this product

Sartorius Octet ARC Biosensors

Description

Sartorius Octet Anti-Rabbit IgG Capture (ARC) Biosensors enable label-free, high-throughput kinetic and quantitation analysis of Fc-containing rabbit IgG antibodies. They are designed for use with crude and purified cell-culture samples in the development and manufacture of rabbit IgG-derived therapeutics. The biosensors provide high ligand-loading capacity and sensitivity and can be regenerated for repeated kinetic and quantitation assays.

Key Features

  • High specificity for Fc-containing rabbit IgG, with minimal to no binding to human, monkey, mouse and rat IgG.
  • Strong binding to rabbit Fc fragment with no binding to rabbit Fab fragment.
  • High ligand-loading capacity and sensitivity.
  • Suitable for high-throughput kinetic and quantitation workflows.
  • Supports analysis of crude and purified samples.
  • Regenerable for repeated kinetic and quantitation assays.

Applications

  • Kinetic analysis of rabbit IgG antibodies.
  • Quantitation of rabbit IgG in crude and purified cell-culture samples.
  • Lead identification and optimisation during antibody development.
  • Cell-line and process development for rabbit IgG-derived therapeutics.
  • Quality-control analysis of crude and purified protein samples.

Specifications

  • Typical quantitation precision: CV <10%.
  • Regeneration: up to 20 times for kinetic and quantitation assays.
  • Analyte specificity: Fc-containing rabbit IgG, including strong binding to rabbit Fc fragment and no binding to rabbit Fab fragment.

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RNAnalytics

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